From the Journal of Nutrition:
A High Intake of trans Fatty Acids Has Little Effect on Markers of Inflammation and Oxidative Stress in Humans
From the abstract:
Consumption of industrial trans fatty acids (iTFA) increases LDL cholesterol, decreases HDL cholesterol, and is strongly associated with a higher risk of cardiovascular disease (CVD). However, changes in circulating cholesterol cannot explain the entire effect………….
Consumption of iTFA caused 4% lower TNF-RI concentrations and 6% higher E-selectin concentrations compared with oleic acid (control) and had no significant effect on other inflammatory markers.
And the end result was that….
In conclusion, high intakes of iTFA and CLA did not substantially affect plasma concentrations of inflammatory markers
Mind you, this study doesn’t go against the conventional wisdom that trans fats are bad for you, but it casts doubt on a particular mechanism through which they might work, inflammatory stress. So they’re still not very well understood, and it’s still possible that the observed effects of trans fats might have other causes.